OnGuard Immune Defense

REFERENCES:

Maitake and Cancer

Effect of Maitake (Grifola frondosa) D-Fraction on the activation of NK cells in cancer patients.
Kodama N, Komuta K, Nanba H. J Med Food. 2003 Winter;6 (4):371-7. PMID: 14977447 [PubMed - indexed for MEDLINE]

Effects of D-Fraction, a polysaccharide from Grifola frondosa on tumor growth involve activation of NK cells.
Kodama N, Komuta K, Sakai N, Nanba H. Biol Pharm Bull. 2002 Dec;25(12):1647-50. PMID: 12499658 [PubMed - indexed for MEDLINE]

Can maitake MD-fraction aid cancer patients?
Kodama N, Komuta K, Nanba H. Altern Med Rev. 2002 Jun;7(3):236-9. Review. PMID: 12126464 [PubMed - indexed for MEDLINE]

Effects of maitake (Grifola frondosa) D-Fraction on the carcinoma angiogenesis.
Matsui K, Kodama N, Nanba H. Cancer Lett. 2001 Oct 30;172(2):193-8. PMID: 11566496 [PubMed - indexed for MEDLINE]

Maitake extracts and their therapeutic potential.
Mayell M. Altern Med Rev. 2001 Feb;6(1):48-60. Review. PMID: 11207456 [PubMed - indexed for MEDLINE]

Induction of apoptosis in human prostatic cancer cells with beta-glucan (Maitake mushroom polysaccharide).
Fullerton SA, Samadi AA, Tortorelis DG, Choudhury MS, Mallouh C, Tazaki H, Konno S. Mol Urol. 2000 Spring;4(1):7-13. PMID: 10851301 [PubMed - indexed for MEDLINE]

The use of mushroom glucans and proteoglycans in cancer treatment.
Kidd PM. Altern Med Rev. 2000 Feb;5(1):4-27. Review. PMID: 10696116 [PubMed - indexed for MEDLINE]

Effect of Maitake D-fraction on cancer prevention.
Nanba H, Kubo K. Ann N Y Acad Sci. 1997 Dec 29;833:204-7. No abstract available. PMID: 9616756 [PubMed - indexed for MEDLINE]

Activity of maitake D-fraction to inhibit carcinogenesis and metastasis.
Nanba H. Ann N Y Acad Sci. 1995 Sep 30;768:243-5. No abstract available. PMID: 8526356 [PubMed - indexed for MEDLINE]

Antitumor activity exhibited by orally administered extract from fruit body of Grifola frondosa (maitake).
Hishida I, Nanba H, Kuroda H. Chem Pharm Bull (Tokyo). 1988 May;36(5):1819-27. No abstract available. PMID: 3203420 [PubMed - indexed for MEDLINE]

Shiitake and Cancer

Inhibition of human colon carcinoma development by lentinan from shiitake mushrooms (Lentinus edodes).
Ng ML, Yap AT. J Altern Complement Med. 2002 Oct;8(5):581-9. PMID: 12470439 [PubMed - indexed for MEDLINE]

Effects of a mushroom mycelium extract on the treatment of prostate cancer.
deVere White RW, Hackman RM, Soares SE, Beckett LA, Sun B. Urology. 2002 Oct;60(4):640-4. PMID: 12385925 [PubMed - indexed for MEDLINE]

Shiitake and Viruses

A placebo-controlled trial of the immune modulator, lentinan, in HIV-positive patients: a phase I/II trial.
Gordon M, Bihari B, Goosby E, Gorter R, Greco M, Guralnik M, Mimura T, Rudinicki V, Wong R, Kaneko Y. J Med. 1998;29(5-6):305-30. PMID: 10503166 [PubMed - indexed for MEDLINE]

Antitumor effect of virus-like particles from Lentinus edodes (Shiitake) on Ehrlich ascites carcinoma in mice.
Takehara M, Mori K, Kuida K, Hanawa MA. Arch Virol. 1981;68(3-4):297-301. No abstract available. PMID: 7271461 [PubMed - indexed for MEDLINE]

Research on Bovine Colostrum

General Benefits

Bovine colostrum offers broad-spectrum benefits for wide-ranging ailments.
Medical Journalist Report of Innovative Biologics: Townsend Letters for Doctors and Patients. Walker M. (1999) 74-80.

Active chromium complex from bovine colostrum help to regulate blood glucose levels.
American Institute of Nutrition. 118(1):39-45. PubMed Reference

Antioxidant properties of colostrum.
Pediatric Research. 24(1):14-9. PubMed Reference

Treatment of severe eye dryness and problematic eye lesions with bovine colostrum. Adv Exp Med Biol. 350:595-9. PubMed Reference

Proline-Rich Polypeptide (PRP) Complex Isolated from Colostrum for Treatment of Alzheimer's Disease.
A Double - Blind Placebo-Controlled Study. Archivum Immunologiae et Therapiae Experimentalis. 47(6):377-85. PubMed Reference

Bovine colostrum has anti-inflammatory benefits and prevents NSAID induced gut damage. Gut. 44:653-658. PubMed Reference

Growth Factors

Effect of growth factors on wound healing.
Journal of Surgery Res. 59:236-244. PubMed Reference

Insuin-like growth factor-1 blood levels are not associated with prostate specific antigen (PSA) levels or prostate cancer:
(Cass TL) A study of 749 patients. Medical College of Wisconsin, Milwaukee, WI www.worldhealth.net/news/prost-igf1/:1999.

Insulin and IGF-1 enhance human skeletal muscle synthesis.
Journal of Clinical Investigations 96:1722-1729. PubMed Reference

IMMUNE FACTORS

Transfer Factors

Structural nature and functions of transfer factors.
Annals New York Academy of Sciences. 685:362-8. PubMed Reference

Cytokines

Cytokines useful in immunodeficient individuals. Journal of Biological Regulators and Homeostatic Agents. 3:121-124. PubMed Reference

Cytokines effect in rheumatoid arthritis. Maruyama H, Nakajima J, Yamamoto I. Kitasato Arch Exp Med. 1987 Sep;60(3):105-21. No abstract available. PMID: 2455094

Bovine colostrum and its antibacterial effect.
Infection and Immunity. 57:1227-1234. PubMed Reference

Proline-rich polypeptide from bovine colostrum benefit the immune system. Immunology. 36:879-881. PubMed Reference

Proline-rich polypeptide (PRP)- from bovine colostrum has an immunomodulatory effect.
Archivum Immunologiae et Therapiae Experimentalis. 41:275-279.

Proline-rich polypeptide from colostrum has immunoregulatory properties. Molecular Immunology. 12:1277-1282. PubMed Reference

Bovine colostrum used for wound healing in vivo.
Science. 219(4590): 1329-31. PubMed Reference

Bovine colostrum containing antibodies to human rotavirus.
Lancet. 2(8665):709-12. PubMed Reference

Prevention of rotavirus infection with bovine colostrum containing antibody against human rotavirus.
Lancet. 2(8357):1029-30. PubMed Reference

Bovine colostrum to treat rotavirus gastroenteritis in infants.
Journal of Infectious Diseases. 156:158-166. PubMed Reference

Immunoglobulin components and anti-viral activities in bovine colostrum.64:274-279. PubMed Reference

IgA from colostrum used to treat E coli. Scandavian Journal of Immunology. 46:59-66. PubMed Reference

Intestinal

Bovine colostrum benefits the human stomach and small intestine.
Gut. 44(2):212-7. PubMed Reference

Bovine colostrum provides passive immunity against diarrhoea.
Acta Paediatr. 85:125-128. PubMed Reference

Treatment of Helicobacter pylori infection with oral immunoglobulins from bovine colostrum.
Ailment Pharmacol Therapies. 12:563-568. PubMed Reference

Helicobacter pylori (H. pylori).
The Journal of Infectious Diseases. 177: 955-961. PubMed Reference

Colostrum benefits the Leaky gut of alcoholism.
The Lancet. 1(8370):179-82. PubMed Reference

Bovine colostrum has anti-inflammatory benefits and prevents NSAID induced gut damage. Gut. 44:653-658. PubMed Reference

Bactericidal effect of bovine colostrum against Helicobactor pylori.
Journal of Applied Bacteriology 78:655-662. PubMed Reference

Treatment diarrhea in AIDS patients with bovine colostrum patients.
AIDS. 4:581-584. PubMed Reference

Bovine colostrum and its effect in the human digestive tract.
ZH Mikrobiology Epidemiology Immunobiology. 9:101-106. PubMed Reference

Bovine colostrum ameliorates diarrhea caused by E coli.
Journal of Pediatric Gastroenterology and Nutrition. 29:452-456. PubMed Reference

Glyconutrient a novel immune-enhancing polysaccharide.
Alternative Medicine Review. 4(2):96-103. PubMed Reference

Colostrums affect against herpes simplex virus.
Journal of Clinical Laboratory Immunology. 1:221-224. PubMed Reference

Low colostral IgA associated with cow's milk allergy.
Acta Pediatr Scan. 80:1207-1213. PubMed Reference

Protective potential of colostrum against prospective influenza viruses.
Journal of Tropical Pediatrics. 36(2):94-5. PubMed Reference

Siber G. (1992) Immune globulin to prevent nosocomial infection.
(Accuaired during hospitalization) New England Journal of Medicine. 327(4):269-71. PubMed Reference

Lactoferrin

Lactoferrin is a lipid A-binding protein.
Infection and Immunity. 62:2628-2632. PubMed Reference

Lactoferrin and it’s functions.
Lactoferrin: Structure and Function. 1-12. PubMed Reference

Lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro.
Journal of Infectious Diseases. 172:380-388. PubMed Reference

Lactoferrin is studied against human herpes virus.
Jpn. Journal of Sci. Biol. 47:73-85. PubMed Reference

Lactoferrin markedly inhibits hepatitis C virus.
Biochemical and Biophysical Research Communications. 245:549-553. PubMed Reference

Lactoferrin: A general review.
Haematologica 3:252-267. PubMed Reference

Effects of bovine Lactoferrin on colon carcinoma 26 lung metastasis in mice. Clinical and Experimental Metastasis. 17:35-40. Masaaki I. and et al. (1999)

Lactoferrin in the human colon carcinoma.
Biochemistry Journal. 308:391-397. PubMed Reference

Anti Viral

Treatment diarrhea in AIDS patients with bovine colostrum patients.
AIDS. 4:581-584. PubMed Reference

Protective potential of colostrum against prospective influenza viruses.
Journal of Tropical Pediatrics. 36(2):94-5. PubMed Reference

Siber G. (1992) Immune globulin to prevent nosocomial infection.
(Accuaired during hospitalization) New England Journal of Medicine. 327(4):269-71. PubMed Reference

Colostrums affect against herpes simplex virus.
Journal of Clinical Laboratory Immunology. 1:221-224. PubMed Reference

Bovine colostrum containing antibodies to human rotavirus.
Lancet. 2(8665):709-12. PubMed Reference

Prevention of rotavirus infection with bovine colostrum containing antibody against human rotavirus.
Lancet. 2(8357):1029-30. PubMed Reference

Bovine colostrum to treat rotavirus gastroenteritis in infants. Journal of Infectious Diseases. 156:158-166. PubMed Reference\

Immunoglobulin components and anti-viral activities in bovine colostrum. 64:274-279. PubMed Reference

Allergies

Low colostral IgA associated with cow's milk allergy.
Acta Pediatr Scan. 80:1207-1213. PubMed Reference

Athletics

Body Composition. Nutrition 17:243-247, 2001. PubMed Reference

Endurance running in marathoners. Medicine and Science in Sports and Exercise. 22: 207-212. PubMed Reference

IGF-1, IgG levels during training. Journal of Applied Physiology.
83: 1144-1151. PubMed Reference

Marathon racing and the effects of fluid replacement, immune function, and psychological factors. Sports Medicine. 15: 116-132. PubMed Reference